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HPV is causing a variety of benign, borderline and malignant disorders, with common anogenital signs. The association of various types of treatment is still human papillomavirus hpv symptoms preferred method to eradicate HPV infection. This paper offers information about possible systemic treatments of HPV infection, based on the documentation from the PubMed databaseincluding immunomodulatory drugs, antiviral medications, therapeutic HPV vaccines and biological therapy. Keywords HPV, HPV systemic treatment, therapeutic vaccines, systemic immunomodulators, systemic antiviral drugs Rezumat Infecţia umană cu diferite genotipuri ale virusului papiloma uman HPV este una dintre cele mai frecvente infecţii virale cu transmitere sexuală.

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The virus infects basal epithelial cells of stratified squamous epithelium. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. Human papillomavirus hpv signs and symptoms High-risk E6 and E7 bind what is human papillomavirus hpv symptoms p53 and pRb and inactivate their functions with dysregulation of the cell cycle. Uncontrolled cell proliferation leads to increased risk of genetic instability.

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Department of Ophthalmology, Grigore T. E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.