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It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL, is associated with helminth infections in both humans and mice. This response is complex and includes effector helminth infections atopy that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, the helminth infections atopy 2 immune response can also mediate tolerance mechanisms, helminth infections atopy can mitigate tissue injury as these large multicellular parasites transit through vital organs. Helminth infections atopy tolerance mechanisms include both tissue repair and immune regulatory effects.
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